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Return to ADDvisor Volume 4 2002 Index

 

Number 2 January 18, 2002

In this issue:

1. New Medications for ADHD

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NEW MEDICATIONS FOR ADHD

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This week, I attended a dinner sponsored by Shire to promote their new ADHD medication, Adderall XR. Adderall XR is a once a day medication similar to Concerta in duration.

Adderall XR is the same formulation as regular Adderall which is a mixture of amphetamine salts. What is different about Adderall XR is the delivery system. Inside of the Adderall XR capsule are tiny beads. Some of these are immediate release beads. They release their medication immediately upon entering the body. The delayed release beads release their medication about 4 hours later. As a result, the medication appears to last up to 12 hours.

Shire recommends that those individuals taking regular Adderall can be switched over to Adderall XR.

This medication adds to the options that are available to manage the symptoms of ADHD.

Also on the horizon is a new non stimulant medication called atomoxetine which is reportedly effective in managing the symptoms of ADHD with fewer side effects. Its release is expected sometime this year.

Eli Lilly (the drug company devloping atomoxetine) researchers state that the medication will have a broader impact on patient functioning as compared to stimulant medication. They report that patients taking atomoxetine function better in family and social situations. Where stimulant medication affects dopamine levels in the brain, atomoxetine impacts norepinephrine, another brain chemical that is indicated to be important in regulating attention and contolling impulses.

Another delivery system for methylphenidate is also under investigation. A transdermal patch is currently in development which may be useful with kids who have difficulty swallowing pills.

Novartis, the makers of Ritalin, have just introduced Focalin, a new formulation of methylphenidate that can be given in half the dosage of Ritalin and is reported to be just as effective.

CONTACT INFORMATION

_____________________________

Alan R. Graham, Ph.D.

Bill Benninger, Ph.D.

ADDvisor.com

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Bill@ADDvisor.com

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